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Rev. cientif. cienc. med ; 23(2): 247-251, 2020.
Article in Spanish | LILACS | ID: biblio-1358632

ABSTRACT

PEl Ácido Valproico (AVP), fármaco ampliamente conocido por sus propiedades antiepilépticas para el manejo de la epilepsias parciales y simples. Es también utilizado dentro de la Psiquiatría como estabilizador del humor y apoyo en el tratamiento de episodios de manía donde el uso del litio está contraindicado. Presentamos el caso de un hombre de 53 años con trastorno esquizoafectivo no especifico y mala adherencia al tratamiento, quien al iniciar manejo con AVP desarrolló una intoxicación por este fármaco, independiente a los niveles en suero de este, revolviéndose con líquidos intravenosos y reajuste de dosis.


Valproic Acid (VA), a widely known medication being used in partial and simple epilepsy treatment because of its antiepileptic properties. It's also used within Psychiatry as a mood stabilizer and the support in the treatment for manic episodes on which lithium its contraindicated. We present the case of a 53-year-old man with nonspecified schizoaffective disorder and poor adherence to treatment, when initiated treatment with VA developed drug toxicity that was independent of VA serum levels, resolving with intravenous fluids and dose readjustment.


Subject(s)
Male , Middle Aged , Drug-Related Side Effects and Adverse Reactions , Psychiatry , Psychopharmacology , Psychotropic Drugs/administration & dosage , Treatment Adherence and Compliance , Anticonvulsants
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